• E1 Ubiquitin like protein complex
• References
• Slides

References

1. Synthesis of bisphosphonate derivatives of ATP by T4 DNA ligase, ubiquitin activating enzyme (E1) and other ligases. Biochemical Pharmacology. Sillero, Maria A. 75: 1959-1965 (2008).

2. The Structure of the APPBP1-UBA3-NEDD8-ATP Complex Reveals the Basis for Selective Ubiquitin-like Protein Activation by an E1. Molecular Cell. Walden, Helen. 12: 1427-1437 (2003).

3. APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP. RCSB Protein Data Bank. http://www.rcsb.org/pdb/explore/explore.do?structureId=1R4N.

4. Dali Server http://ekhidna.biocenter.helsinki.fi/dali_server/start

5. Expasy. Swiss Institute of Bioinformatics. http://ca.expasy.org/tools/#proteosome

6. NCBI Protein Blast http://www.ncbi.nlm.nih.gov/blast/Blast.cgi?PAGE=Proteins&PROGRAM=blastp

7. Basis for a ubiquitin-like protein thioester switch toggling E1?E2 affinity. Nature. Huang, Danny T. 445: 394-398 (2007).

8. COMMD1 promotes the ubiquitination of NF-B subunits through a cullin-containing ubiquitin ligase. The EMBO Journal. Maine, Gabriel N. 26: 436-447 (2007).

9. Structural Insights into E1-Catalyzed Ubiquitin Activation and Transfer to Conjugating Enzymes. Cell. Lee, Imsang. 134: 268-278 (2008).

10. Structural Insights into NEDD8, Activation of Cullin-RING Ligases: Conformational Control of Conjugation. Cell. Duda, David. 134: 995-1006 (2008).